Publications
The Cost of Drug Shortages
16 September 2024
Across the globe, drug shortages are becoming increasingly common.
Unlocking the Value of Combination Therapies
9 July 2024
Combination therapies (CTs) merge treatments with different mechanisms of action to achieve greater clinical benefits than the individual components alone. CTs are increasingly being used in oncology.
Inequalities in Dementia: Unveiling the Evidence and Forging a Path Towards Greater Understanding
26 June 2024
Our literature review suggests that there are more than 100 inequalities impacting on people living with dementia and their carers across multiple characteristics, circumstances, and in various parts of the health and care system. However, the current low availability and quality of data is a major barrier to accurately measuring these inequalities. With the expectation that 1 in 2 people will be affected by dementia during their lifetime, there is a pressing need for further research to inform future policy, research, and service interventions.
A Framework for Value-aligned Pricing of Combination Therapies
25 June 2024
Combination therapies can provide effective treatment options and improve patient outcomes. However, there are significant barriers to patient access to combination therapies, including the prevailing pricing models used in Europe.
How Have HTA Agencies Evolved Their Methods Over Time?
29 April 2024
The many changes in Health Technology Assessment (HTA) methods and processes over time, are a challenge to navigate let alone stay abreast of. This report explores the breadth of variation in past and current positioning of HTA agencies in 14 countries, on five key methodological topics: discount rates, modifiers, patient involvement, real-world evidence (RWE), and surrogate endpoints.
Socio-Economic Value of Adult Immunisation Programmes
18 April 2024
Adult vaccines can return up to 19 times their initial investment to society, when their significant benefits beyond the healthcare system are monetised.
Incorporating the Patient Voice in Health Technology Assessment
15 February 2024
The decision to adopt or not adopt a new healthcare technology, and the process by which this decision is made, affects patients, the health system, and wider society. In this Whitepaper, we suggest that the patient perspective is critical to making fully-informed decisions about the value of new technologies, but this perspective has not always been given the same weight as clinical and economic aspects in health technology assessment (HTA).
Developing a Conceptual Framework of Healthcare System Pressure
13 February 2024
The term ‘pressure’ has been widely used to describe various challenges, long before the COVID-19 pandemic. Regardless of its common usage, a formal definition of healthcare system pressure (HCSP) is currently missing.
The Socioeconomic Burden Of Cervical Cancer in the UK: What are the benefits of achieving the WHO elimination target?
24 January 2024
Cervical cancer imposes a substantial burden on patients, their support networks, the NHS, and society at large. This report underscores the significant socioeconomic savings that can be achieved by reaching the WHO’s elimination goal of 4 cases per 100,000 women, providing further impetus to take action to reach the ambitious 2040 elimination target set by NHS England.