Publications

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Addressing the systemic challenges of underinvestment in prevention

8 June 2026

Prevention of ill-health is an underexploited tool for protecting health systems and societies. It offers the potential to curb increasing demand for healthcare services, increase participation…

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The impact of inflation on incremental costs in HTA

4 June 2026

Inflation reshapes the economic landscape in which new treatments are evaluated. Yet cost-effectiveness thresholds tend to remain fixed over time. This report examines how inflation in…

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The value of fast diagnostics in time-critical infections

20 April 2026

Advancing earlier intervention in time‑critical infections Sepsis continues to impose a substantial global burden, with millions of cases and high mortality each year. Patients with bloodstream…

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Evaluating novel antimicrobials within EU joint clinical assessments 

16 April 2026

Antimicrobial resistance (AMR) is a growing global health and economic threat. It is responsible for an additional 9.5 million hospital days and costs across the European Union (EU) and European Economic Area (EEA) economies €11.7 billion annually.

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The burden of LDL-cholesterol-driven atherosclerotic cardiovascular diseases

31 March 2026

Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of morbidity and mortality globally, and is responsible for substantial health and economic burden to health systems and wider society.

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The case for adopting a broader perspective on value in Health Technology Assessment

3 March 2026

In this Whitepaper, we describe different perspectives that can be adopted in Health Technology Assessment (HTA), and some of the advantages and disadvantages of these different…

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Novel devices: optimising drug delivery in multiple myeloma

9 December 2025

Biologics: Driving innovation in the treatment of multiple myeloma Biological medicines (biologics) have transformed the treatment landscape of multiple myeloma and cancer as a whole. The…

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A global landscape analysis of access to tumour-agnostic therapies 

1 December 2025

Tumour-agnostic (TA) therapies represent a paradigm shift in oncology by targeting molecular alterations regardless of tumour histology.

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Capturing the lived experiences of informal care in acute leukemia

20 November 2025

Providing informal care to someone living with acute leukemia imposes a severe multidimensional burden, reshaping relationships and affecting mental health, physical health, career, finances, social activities and more.