Chronic Diseases

Chronic diseases are long-lasting (or slowly emerging) conditions, often requiring ongoing medical attention and featuring periods of remission and relapse. A rapid rise in chronic diseases has imposed great health, social, and economic costs, as well as contributing to an overburdened healthcare system.

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Insights

The cost of inaction on LDL cholesterol

24 June 2026

This Insight is based on the WHA79 panel discussion “Lowering Cholesterol, Increasing Impact: The Case for Earlier Action to Address the CV Epidemic”, co-organised by OHE and MSD, at the World Health Assembly in Geneva, May 2026.

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Insights

Why do we expect obesity medicines to work differently?

5 March 2026

Weight regain after stopping GLP-1 medicines isn’t a treatment failure — it shows that obesity is a chronic, relapsing condition. Like other long-term therapies, benefits last only while treatment continues. Reframing obesity this way can improve outcomes and reduce stigma.

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Publication

The case for adopting a broader perspective on value in Health Technology Assessment

3 March 2026

In this Whitepaper, we describe different perspectives that can be adopted in Health Technology Assessment (HTA), and some of the advantages and disadvantages of these different…

Top view of Highway road junctions at night The Intersecting fr
Publication

Novel devices: optimising drug delivery in multiple myeloma

9 December 2025

Biologics: Driving innovation in the treatment of multiple myeloma Biological medicines (biologics) have transformed the treatment landscape of multiple myeloma and cancer as a whole. The…

A stethoscope laying on a map
Publication

Altering the trajectory of HIV in Europe

22 May 2025

Despite substantial medical advancements that have transformed HIV into a manageable chronic condition for individuals, the epidemic remains a pressing public health concern in Europe.

Publication

Understanding the Full Value of Long-Acting Therapies: less is more?

7 May 2025

Long-acting (LA) therapies represent a significant innovation in pharmaceutical development by offering a sustained drug effect with reduced administration frequency.

Insights

Advancing Rare Disease Care: Challenges and Key Issues

28 February 2025

Today marks Rare Disease Day 2025. This time last year we published an Article entitled “ Why do we care about rare?”, summarising the origins of…

Insights

OHE’s submission for the DHSC’s next 10 years of planning

9 December 2024

This Insight summarises the recommendations OHE submitted towards the Department of Health & Social Care’s consultation on the next 10 years of planning for the NHS.

Publication

A Spotlight on Haemophilia Therapies

3 October 2024

Pharmaceutical innovation is a key driver of improvements in health outcomes, quality of life and productivity for people with acute and chronic conditions.