Publications

Employer Costs from Respiratory Infections

16 December 2024

Our latest research shows respiratory infections cost UK businesses £44 billion a year. Workplace vaccination programs and health-focused policies could help boost productivity, reduce costs, and address health inequities.

Understanding societal preferences for priority by disease severity in England & Wales

14 November 2024

How does NICE’s severity modifier work? NICE implemented a new severity modifier in February 2022 as part of a wider update to its methods. Its aim…

A Spotlight on Haemophilia Therapies

3 October 2024

Pharmaceutical innovation is a key driver of improvements in health outcomes, quality of life and productivity for people with acute and chronic conditions.

Three rows of identical orange prescription bottles with white lids and labels, arranged neatly in a line, increasing in height from left to right against a white background.

The Cost of Drug Shortages

16 September 2024

Across the globe, drug shortages are becoming increasingly common.

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Unlocking the Value of Combination Therapies

9 July 2024

Combination therapies (CTs) merge treatments with different mechanisms of action to achieve greater clinical benefits than the individual components alone. CTs are increasingly being used in oncology.

A human head paper cut out with tangled red yarn above symbolising the brain

Inequalities in Dementia: Unveiling the Evidence and Forging a Path Towards Greater Understanding

26 June 2024

Our literature review suggests that there are more than 100 inequalities impacting on people living with dementia and their carers across multiple characteristics, circumstances, and in various parts of the health and care system. However, the current low availability and quality of data is a major barrier to accurately measuring these inequalities. With the expectation that 1 in 2 people will be affected by dementia during their lifetime, there is a pressing need for further research to inform future policy, research, and service interventions.

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A Framework for Value-aligned Pricing of Combination Therapies

25 June 2024

Combination therapies can provide effective treatment options and improve patient outcomes. However, there are significant barriers to patient access to combination therapies, including the prevailing pricing models used in Europe.

How Have HTA Agencies Evolved Their Methods Over Time?

29 April 2024

The many changes in Health Technology Assessment (HTA) methods and processes over time, are a challenge to navigate let alone stay abreast of. This report explores the breadth of variation in past and current positioning of HTA agencies in 14 countries, on five key methodological topics: discount rates, modifiers, patient involvement, real-world evidence (RWE), and surrogate endpoints.

Socio-Economic Value of Adult Immunisation Programmes

18 April 2024

Adult vaccines can return up to 19 times their initial investment to society, when their significant benefits beyond the healthcare system are monetised.