Research Papers

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Can Transparency Lower Prices and Improve Access to Pharmaceuticals? Not So Fast…

28 March 2019

Report does not recommend price transparency for on-patent medicines, but buyers should share multi-source product price data among themselves. Transparency of the procurement process encourages bidders.…

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Exploring Variations in the Opportunity Cost Cost-effectiveness Threshold by Clinical Area: Results from a Feasibility Study in England

20 March 2019

Estimating a cost-effectiveness threshold reflecting the opportunity cost of adopting a new technology in a health system is not easy. A new OHE report provides empirical…

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Abolishing Pharmaceutical Rebates in the US? Looking at the Trade-Offs

12 March 2019

The combination of rising drug costs in the US and increasing financial stress for individual patients has triggered intense national concern. One target has come under…

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Opportunity Costs of New Health Care Technologies: A Research Agenda

8 August 2018

A new OHE Research Paper sets out an agenda for the development of methods to estimate cost-effectiveness thresholds in the NHS.

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Incentives, Competition, and Pharmaceutical Innovation in Europe: The Case of Direct Acting Antivirals for Hepatitis C

26 July 2018

To what extent can R&D incentives, competition and other factors facilitate access to highly valuable and costly pharmaceutical innovations?

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How Much Should Society Pay for a New Orphan Drug? A Contribution to this Debate is now Available in a New OHE Research Paper

18 July 2018

What would be the price for an orphan drug that generate rates of return no greater/smaller than the industry average? Is it reasonable?

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What are the Economic Implications of Moving Away from Paying a Single Price for a Single Drug?

9 July 2018

The OHE has published a report exploring the impact on payers, patients and innovators of differential prices for different uses of pharmaceuticals.

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New Publications: Optimal Development and Use of Real-World Evidence for Coverage and Formulary Decisions

18 April 2018

Just published are two new reports that explore the use of real world evidence for coverage and formulary decisions. The publications represent 1) the background paper…

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New Methods for Analysing the Distribution of EQ-5D Observations

17 April 2018

Our latest OHE Research Paper presents new methods for summarising EQ-5D data from patients.