Publications
The Current Drug Development Paradigm: Responding to US and European Demands for Evidence of Comparative Effectiveness and Relative Effectiveness
1 April 2014
The project reported in this Occasional Paper was intended to determine how changing demands for evidence are affecting drug development in five global pharmaceutical companies: Amgen,…
Real Option Value and Path Dependence in Oncology Innovation
1 April 2014
Based on an OHE Lunchtime Seminar, this publication addresses a persistent issue: how to adequately reward innovation through the pricing of new medicines given the limitations…
Can the US Afford to Ignore Cost-effectiveness Evidence?
1 March 2014
Cost-effectiveness analysis plays a limited role in US health care compared to many other countries. In this Seminar Briefing, Dr James Chambers, Center for the Evaluation…
Projecting Expenditure on Medicines in the NHS: Second Edition
1 January 2014
The Pharmaceutical Price Regulation Scheme (PPRS) 2014 Heads of Agreement, announced on 6 November 2013, outlines the terms of the five-year deal between the pharmaceuctical industry…
Contracting for Quality in the NHS
1 January 2014
This monograph, based on Professor Maynard’s remarks at the 20th OHE Annual Lecture, explores the critical issue of ensuring the quality of care in the NHS.…
Searching for Cost-effectiveness Thresholds in NHS Scotland
1 December 2013
This research examines the use of QALY thresholds in NHS Scotland in 2012-13 for health services that were “at the margin”, i.e. those for which investment or…
Critique of CHE Research Paper 81: Methods for the Estimation of the NICE Cost Effectiveness Threshold
12 January 2013
This paper counters the recently-published recommendation by Claxton et al[1] that NICE should lower its cost-per-QALY threshold from the current £20,000–£30,000 official range to £12,936. The…
The Influence of Cost-effectiveness and Other Factors on NICE Decisions
1 November 2013
In this Research Paper, the authors explore which factors have most influenced NICE decisions from 1999 through the end of 2011. The research has two objectives:…
OHE Guide to UK Health and Health Care Statistics
1 October 2013
This publication provides both up-to-date statistics and a guide to finding and using health statistics from the UK and, to some extent, other OECD countries. Data…