Drug Development/R&D

New medicines lead to improved patient outcomes and societal benefits, but R&D is a long and costly process. Ongoing health economics research aims to find the right balance between incentivising manufacturers to innovate and ensuring affordable access for health systems.

Invest to End TB. Save Lives. World TB Day 2022. Reflections on 60 years of OHE publications on TB
Insights

Invest to End TB. Save Lives. World TB Day 2022. Reflections on 60 years of OHE publications on TB

24 March 2022

Global TB deaths are increasing. CGD and OHE set out a “Market-Driven, Value-Based, Advance Commitment (MVAC)” that would create and guarantee a market for a breakthrough…

Pills on shopping cart Macro A variety of tablets and medicines in a mini shopping cart Medecine concept
Insights

How Does Pharmaceutical Spending Drive Innovation in Europe?

7 February 2022

A new publication by Kourouklis and Gandjour (2022) investigates the impact of pharmaceutical spending on domestic early-stage pharmaceutical innovation in Europe. They find that European spending…

Limitations of CBO’s Simulation Model of New Drug Development as a Tool for Policymakers
Publication

Limitations of CBO’s Simulation Model of New Drug Development as a Tool for Policymakers

1 June 2022

In recent years, U.S. policymakers have been considering reforms to tackle high and rising prescription drug spending, including unprecedented direct limits on prices and price growth…

Event

Virtual OHE Annual Lecture 2021: Do Patents Work? Evidence from Pharmaceutical Innovation

28 September 2021

The exceptional circumstances of COVID-19 revived the controversy around patents of pharmaceutical products. A group of specialists suggested that the Trade-Related Aspects of Intellectual Property Rights…

Close-up of a glass pipette releasing a droplet over a row of test tubes in blue and red neon lighting.
Insights

How Should the World Pay for a Coronavirus Disease (COVID-19) Vaccine? Where are we 6 Months on?

1 July 2021

The Value in Health May issue includes the paper “How Should the World Pay for a Coronavirus Disease (COVID-19) Vaccine?”. Finalised in December 2020, it includes:…

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Insights

Towards a New Understanding of Unmet Medical Need

22 June 2021

In a commentary piece recently published in Applied Health Economics and Health Policy, OHE authors discuss how the misalignment in interpretations of the term ‘unmet medical…

Close-up of a glass vaccine vial labeled COVID-19 in focus, with blurred rows of similar vials in the background on a blue surface.
Insights

Would Waiving COVID-19 Vaccines Patents Save Lives?

18 May 2021

This blog discusses the rationale behind a COVID-19 patent waiver decision and contributes to the current debate by producing a balanced view on the benefits and…

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Insights

Does Government Funding Increase Public Sector Development of New Medicines?

5 March 2021

Looking at public sector drug development in Europe, this paper suggests that government funding does have an impact on the research and development pipeline, particularly at the earlier stages of research for medicines targeting rare diseases.

Publication

Payment Models for Multi-Indication Therapies

1 November 2021

For the growing number of multi-indication medicines, access may be delayed or even denied due to challenges in linking payment with a medicine’s value across those…