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Ethical and Economic Issues in the Appraisal of Medicines for Ultra-rare (or Ultra-orphan) Conditions
13 January 2020
In light of concerns that not all medicines for ultra-rare (also known as ultra-orphan) conditions are appraised under the same NICE process, a new OHE Consulting Report discusses the distinct…
From the Antipodes to the Motherland: Reflections on HTA Decision Makers as Budget Takers and Budget Makers
19 January 2016
…it is time that the National Institute for Health and Care Excellence (NICE) revisited its processes or, more specifically, its criteria for making decisions. In the current austere climate one…
Dr Francois Maignen joins the OHE team as Head of Operational Research and Data Analysis
7 July 2016
…(NICE). He advised companies on the clinical development of new technologies in various therapeutic areas (mainly oncology, cardiovascular, neurology ad orphan diseases) both in the framework of NICE, SEED (Shaping…
Cost-Effectiveness Thresholds and Expert Elicitation: a Bridge Too Far?
29 April 2021
…In England, if the price and effectiveness of a new technology reviewed by the National Institute for Health and Care Excellence (NICE) means the NHS pays less than a threshold…
Advancing Rare Disease Care: Challenges and Key Issues
28 February 2025
…cell therapies, as well as the “coverage with evidence development” approach adopted by NICE in the UK recently to support access to an innovative gene therapy for sickle cell disease…
Limits to Using QALYs in Cancer
3 August 2010
…to assess the value of medical interventions and may be used in decisions about allocating health care resources. In the UK for example, NICE uses QALYs to ‘compare different drugs…
QALYs v. Other Criteria in NHS Decisions
17 May 2011
…NICE. If important differences exist, the efficiency of resources allocation may be affected negatively. Just released is an OHE Research Paper that examines whether and how decisions about allocating resources…
OHE in the Spotlight: Summer 2011
22 September 2011
…Programme. Held at NICE and led by the University of York’s Centre for Health Economics, the workshop’s purpose was to discuss when NICE should recommend the use of health technologies…
Social Preferences and Burden of Illness in Value-based Assessments
11 February 2014
…2014 in NICE’s methods of value assessment. NICE may replace the existing system of QALY multipliers for end-of-life patients with a more detailed system of burden-of-illness weights derived from the results…