Economics of Innovation

Optimal innovation balances willingness and ability to pay with the benefits of future R&D. Our wide-ranging programme aims to promote innovation in health care, increase our understanding of its value, and encourage R&D. New models of innovation should streamline development, reduce costs, and speed patient benefit.

The Case for Expanding Uptake of Next-Generation Sequencing for Lung Cancer in Europe
Publication

The Case for Expanding Uptake of Next-Generation Sequencing for Lung Cancer in Europe

2 June 2023

In this report, we explore the status of access and uptake for NGS testing for lung cancer in Europe, develop the health economic case for NGS testing, and identify barriers and opportunities for widespread access.

News

Professor Aidan Hollis wins first £40,000 OHE Policy Innovation Prize

25 January 2023

Entrants challenged to devise a globally applicable approach to fair pricing of medicines. Winning entry proposes de-linking the innovation reward payments from the price.

Insights

G7 Investments in New Antibiotics Would Pay Off – For Everyone

9 December 2022

Programs to incentivise antibiotic R&D are underway in the UK and under consideration in the US, EU, Canada, and Japan. We have assessed the benefits and costs to the members of the G7/EU and project that all G7/EU members would see big payoffs ranging from 11:1 in the UK to 28:1 for the US and Japan. Global returns from reducing the 1.27m people dying each year from AMR are even higher.

The World Needs New Antibiotics. A Proposed US Program to Develop Them Offers a High Pay-Off
Insights

The World Needs New Antibiotics. A Proposed US Program to Develop Them Offers a High Pay-Off

16 November 2022

A Center for Global Development (CGD) paper authored by OHE’s Adrian Towse and CGD’s Rachel Silverman Bonnifield shows a very high expected return on investment (ROI)…

The Dynamics of Drug Shortages
Insights

Estimating the Impact of U.S. Drug Price-setting Policies on Innovation Is Challenging, Even for the Congressional Budget Office

22 June 2022

Since the Office of Health Economics (OHE) published a critique of CBO’s new simulation model of new drug development late last year, the U.S. public sector…

Event

Collaborating on Payment Models to Unlock the Potential of Multi-Indication Therapies.

22 June 2022

Innovation in drug development is evolving at pace. Individual medicines are increasingly found to benefit patients in a range of indications….

Invest to End TB. Save Lives. World TB Day 2022. Reflections on 60 years of OHE publications on TB
Insights

Invest to End TB. Save Lives. World TB Day 2022. Reflections on 60 years of OHE publications on TB

24 March 2022

Global TB deaths are increasing. CGD and OHE set out a “Market-Driven, Value-Based, Advance Commitment (MVAC)” that would create and guarantee a market for a breakthrough…

Cracks through the ice on a melting glacier in Alaska
Insights

How Does Pharmaceutical Spending Drive Innovation in Europe?

7 February 2022

A new publication by Kourouklis and Gandjour (2022) investigates the impact of pharmaceutical spending on domestic early-stage pharmaceutical innovation in Europe. They find that European spending…

Limitations of CBO’s Simulation Model of New Drug Development as a Tool for Policymakers
Publication

Limitations of CBO’s Simulation Model of New Drug Development as a Tool for Policymakers

1 June 2022

In recent years, U.S. policymakers have been considering reforms to tackle high and rising prescription drug spending, including unprecedented direct limits on prices and price growth…