Grant-Funded Research

Research Papers are the results of OHE’s grant-funded research programmes intended to promote discussion and provide information prior to publication in a peer reviewed journal

Individual, Health System, and Societal Impacts of Anti-seizure Medicine Use During Pregnancy
Publication

Individual, Health System, and Societal Impacts of Anti-seizure Medicine Use During Pregnancy

23 January 2024

Explore the implications of in utero exposure to anti-seizure medications (ASMs), the heightened risks of developmental problems and physical disabilities. The economic impact associated with conditions like epilepsy, stressing the urgent need for detailed risk profiles and data collection to guide interventions and reduce the societal costs linked to ASM use during pregnancy.

Publication

2022 OHE Annual Report to the Charity Commission

30 November 2023

This is the sixth report to the Charity Commission for England and Wales since becoming a registered charity in December 2016.  

Publication

2021 OHE Annual Report to the Charity Commission

1 December 2022

OHE obtained its charitable status in 2016, an essential achievement towards OHE’s development as a health economics research organisation. The report of 2021 demonstrates some of…

It Takes Two to Tango: When do Conditional Reimbursement Risk-Sharing Schemes Work for Both Parties?
Publication

It Takes Two to Tango: When do Conditional Reimbursement Risk-Sharing Schemes Work for Both Parties?

1 December 2021

Faster regulatory approval has not necessarily achieved faster patient access. A new OHE paper sets out how risk-sharing can tackle this, enabling resolution of differences of…

Making Outcome-Based Payment a Reality in the NHS. Phase Two: Practical Considerations
Publication

Making Outcome-Based Payment a Reality in the NHS. Phase Two: Practical Considerations

1 December 2021

Outcome-based payment (OBP) is a flexible payment mechanism linking the price the NHS pays for a medicine to the outcomes it achieves in practice for NHS…

Publication

Resource Allocation in Public Sector Programmes: Does the Value of a Life Differ Between Governmental Departments?

1 February 2021

This research paper examines whether value of a life estimates used in economic evaluation differs between government departments in a selection of developed countries. The authors find that generally estimates used in transport and the environment exceeded those used in health, which suggests that health may be undervalued by departments of health compared to departments of transport or environment.

Drop Dead: Is Anchoring at ‘Dead’ a Theoretical Requirement in Health State Valuation?
Publication

Drop Dead: Is Anchoring at ‘Dead’ a Theoretical Requirement in Health State Valuation?

1 November 2020

By convention, values for generic ‘preference-based’ measures, such as the EQ-5D, are anchored at 1 = full health and 0 = dead. This paper challenges the…

Cornerstones of “Fair” Drug Coverage: Appropriate Cost - Sharing and Utilization Management Policies for Pharmaceuticals
Publication

Cornerstones of “Fair” Drug Coverage: Appropriate Cost – Sharing and Utilization Management Policies for Pharmaceuticals

1 September 2020

In the focus on US drug prices, ICER has contributed thinking on determining when price aligns with patient benefits. Less debated is whether insurance coverage provides…

Publication

The BRAVE Initiative: The BRAVE Narrative for Broad Recognition of Value in Vaccines Engagement

1 September 2020

Vaccines are widely regarded as one of the most important public health achievements of the last century. Health economists, however, have long highlighted the gaps between…