The NICE methods review consultation included a proposal to consider health inequalities more explicitly in their Health Technology Assessment process. But there is still a long way to go before NICE finds a way to tackle all the complexity of this concept. In the following sections we provide an overall view of the main challenges

Priority setting in health is an important, and sometimes controversial topic. In practice, many health technology assessment agencies give a higher weighting to treatments with ‘desirable’ characteristics. For example, treatments for severe and/or rare diseases. In this blog, we review changes to NICE’s manual to include a new ‘severity modifier’.

We live in a world facing many interrelated challenges, and the choices we make about allocating public sector resources have never been more consequential. The perspective taken in an economic evaluation determines the costs and outcomes included in that evaluation and therefore shapes resource allocation and access to new treatments. In this blog, we review the (lack of) changes to NICE’s manual to include elements of a ‘societal perspective’.

Carer quality of life impacts can be included in health technology evaluations, however little guidance is provided. NICE considered providing more guidance as part of their recent methods review. Ultimately, a set of ‘minimum evidence requirements’ were produced, but these were not included...

This blog post is the second in a series on the new National Institute for Health and Care Excellence (NICE) health technology evaluation manual. Each post provides a critical discussion on a particular topic, including the expected implications of the changes (or lack thereof) in the manual; what is still missing; and what further research is needed.

OHE opens a series of blog posts on the NICE new health technology evaluation manual.

A paradigm shift is occurring in cancer care with the introduction of tumour-agnostic therapies, for which the indication is defined by the molecular signature of the tumour rather than by its location. While promising for patients, healthcare systems are facing major challenges with the clinical and economic assessment of such therapies and subsequent reimbursement decisions.

OHE publishes a research report sponsored by CRUK on the practical considerations for outcome-based payment in the NHS

This blog summarises an initiative taken by more than 300 health economists and experts in support of the creation of an independent health technology assessment agency in Spain.

This blog post summarises some of the more notable changes put forward in NICE’s methods consultation (November – December 2020), and comments on their potential consequences.


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