Search results for: Drug Development/R
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Estimating the Impact of U.S. Drug Price-setting Policies on Innovation Is Challenging, Even for the Congressional Budget Office
22 June 2022
…on incentives to invest in R&D and the risks in drug development is a challenging task. Peer-reviewed literature documenting the relationship between industry revenues and drug development is limited and…
The Inflation Reduction Act: Price negotiation underway for the first 10 drugs
29 November 2023
…Available at: https://pharmaphorum.com/news/novartis-hits-back-entresto-selection-medicare-list [Accessed 5 Sep. 2023]. Wingrove, P., 2023. Drugmakers brace for list of first 10 drugs for US price negotiations. Reuters. [online] 2 Aug. Available at: https://www.reuters.com/sustainability/boards-policy-regulation/drugmakers-brace-list-first-10-drugs-us-price-negotiations-2023-08-02/ [Accessed 30 Aug. 2023]….
Rare Disease Day 2024: Why Do We Care About Rare?
29 February 2024
…drugs. They found that the “standard” £20K/QALY threshold would need to increase to £78K/QALY for orphan drugs (for rare diseases of “average” rarity) and £937K for ultra-orphan drugs. While an…
The Cost of Drug Shortages
16 September 2024
…impacts of drug shortages. Sustainable drug markets are needed to promote resilient supply chains, reducing the risk of drug shortages and benefitting all stakeholders. Share this: Download publication Shortages have…
The Dynamics of Drug Shortages
9 January 2024
…driver of drug shortages, often underlying the causes of drug shortages. Drug shortages can have a large economic and health impact on patients. The duration of shortages has either increased…
Establishing a Reasonable Price for an Orphan Drug
11 September 2020
…and non-orphan drugs have to be considered to determine the reasonable price: (i) costs of research and development are likely to be lower for orphan drugs, and (ii) treatment populations…
Drug shortages are on the rise – but what is their impact?
16 September 2024
…Drug Shortages on Consumer Costs. [online] ASPE. Available at: https://aspe.hhs.gov/reports/drug-shortages-impacts-consumer-costs [Accessed 13 Dec. 2023]. Cancer Research UK, 2024. Trastuzumab. [online] Available at: https://www.cancerresearchuk.org/about-cancer/treatment/drugs/trastuzumab [Accessed 13 May 2024]. Crow, D., 2018. Saline investigation highlights the…
How Much Should Society Pay for a New Orphan Drug? A Contribution to this Debate is now Available in a New OHE Research Paper
18 July 2018
…Pharmacoeconomics, 33(3), 255-269. Meekings, K. N., Williams, C. S., & Arrowsmith, J. E. (2012). Orphan drug development: an economically viable strategy for biopharma R&D. Drug discovery today, 17(13), 660-664. …
Establishing a Reasonable Price for an Orphan Drug
1 July 2018
…of drugs for rare diseases (‘orphan drugs’) has generated considerable debate. While there is debate in the economic literature over whether a premium should be paid for ‘rarity’, these drugs…