Mestre-Ferrandiz, J., Garau, M., O'Neill, P. and Sussex, J.
This report examines the effect of the European Union’s 1999 Regulation on Orphan Medicinal Products (OMPs) on the European economy and society. This study collected data on several indicators of activity, completed a confidential survey of companies developing OMP, concluded four case studies and undertook a literature review. The result is a rich tableau of data and information that describe the effects of the OMP Regulation in some detail. Findings include the following.
In December 2006, the National Institute for Health and Clinical Excellence (NICE) issued guidance for preventing and managing overweight and obesit. Recommendations are step-wise, starting with lifestyle changes and progressing through medicine to bariatric surgery. The guidance recommends that patients considered for bariatric surgery have either a BMI of 40 or more, or a BMI over 35 with an associated condition such as diabetes. Costing guidelines are included in the guidance.
This research reviews how vaccines other than for travel or influenza are evaluated, procured and delivered in Australia. It includes observations as to whether and how the economic assessment process differs for vaccines compared to curative pharmaceutical products and implications of central purchasing for economic efficiency.
This research reviews how vaccines other than for travel or influenza are evaluated, procured and delivered in the UK. It includes observations as to whether and how the economic assessment process differs for vaccines compared to curative pharmaceutical products and the implications of the current pricing approach.
Antimicrobial resistance (AMR) to drugs, a natural and unavoidable consequence of treating infectious diseases, is a growing global public health threat. The EU Commission is to develop comprehensive proposals by the end of 2012 for addressing the situation. This Paper is meant to provide input into those policy discussions.
The paper reviews AMR’s implications for the burden of disease, the causes of AMR, the current state of the antibiotic development pipeline and the reasons antibiotic R&D has been de-emphasised by biopharmaceutical companies.
Research spillovers may exist when research by one organisation creates increased output for other organisations that operate in the same or another sector of the economy. Both the mechanisms and the ultimate value of this transfer of ideas, knowledge or know-how still are not fully understood and virtually all such research on spillovers has been focused outside the UK. Given current constraints on public, charitable and private research funding, enhancing spillovers may become an important objective in UK science and technology policy.
The speaker for the OHE’s 17th Annual Lecture was Dr Alan Garber, Director both of Stanford University’s Center for Health Policy and its Center for Primary Care and Outcomes Research at the School of Medicine. His remarks focused on the national health care legislation enacted in March 2010 in the US from a unique perspective – as a practicing professor of medicine, one of the world’s leading health economists, and an expert in health care policy. His overview touched on several of the key issues raised by the new law that relate to coverage, cost, and quality.
In 2009, the English NHS began collecting patient-reported outcome measures (PROMs) for four elective procedures. Using a series of structured questions that ask patients about their health from their point of view, PROMs are intended to enable the patient perspective to inform decision-making at all levels of the NHS.
This study compares pricing and reimbursement (P&R) policy for 43 orphan medicinal products (OMPs) across seven EU Member States: France, Germany, Italy, The Netherlands, Spain, Sweden and the UK. Examined in particular are the standards of evidence and the criteria for P&R decisions, the availability of access before full licensing approval, and requirements for studies after the drug is available on the market.