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Challenges and Opportunities for Improving Benefit-Risk Assessment of Pharmaceuticals from an Economic Perspective
1 August 2008
This Briefing reports the discussions of a group of experts at an OHE workshop on the benefit-risk assessments of drugs. The objective was to identify how particular tools and methods…
AIDS: Worldwide Policies and Problems
1 September 1991
…first medical reports, relating to a cluster of cases among homosexual men in… The condition which was later to be called AIDS emerged in the early 1980s in several widely…
The Impact of Behavioural and Biomedical Advance on Health Trends over the Next 25 Years
11 January 1994
…of the potential for reducing the burden through behavioural and biomedical advance. The reports addressed these specifically, firstly health gains (and, to the extent possible, cost savings) likely to arise…
Drivers of the Growth in Medicines Expenditure
1 October 1997
…causes of these increases in the UK. It reports on a study carried… Increases in expenditure on medicines, above the level of increases in health care expenditure generally, are a…
Valuing Health-Related Quality of Life: An EQ-5D-5L Value Set for England
1 January 2016
This paper reports the methods and findings from the EQ-5D-5L value set for England study. The value set is derived from the stated preference data of 996 members of the…
Important Aspects of Health Not Captured by EQ-5D: Views of the UK General Public
12 January 2016
This Research Paper reports the views of 179 members of the UK general public about important aspects of health that they consider to be missing from the five dimensions of…
Extrapolation from Progression-Free Survival to Overall Survival in Oncology
1 December 2016
This Research Paper reports on a literature review of trials using PFS as a surrogate for OS in oncology between 2012 and 2016; a workshop and interviews involving people from…
The changing role of the NHS over time
14 August 2023
OHE has been producing reports since 1962 which give insights into issues facing the NHS in the 75 years since it was created. The first part of this blog series,…
Breaking the European Deadlock: Part 3 – Revenue Guarantee and Subscription Models for New Antibiotics
16 January 2024
…Panel on Antimicrobial Availability, CCA. Available at https://cca-reports.ca/reports/pull-incentives-for-high-value-antimicrobials/ European Commission, European Health and Digital Executive Agency, Study on bringing AMR medical countermeasures to the market – Final report, Publications Office of…