OHE Lunchtime Seminars: Steven Pearson and Janel Hanmer

OHE will be hosting two lunchtime seminars this month.

OHE Lunchtime Seminar with Steven Pearson on ‘Early experience with HTA of gene therapies in the US: pricing and paying for cures’. To be held on 22nd October 2018 from 12 p.m. to 2 p.m.

The time is rapidly approaching when health care funders and health care systems around the world must be able to manage a growing number of drugs offering potential cures for a wide range of illnesses. The innovation pipeline includes potential cures for haemophilia, sickle cell disease, and numerous other genetically-based conditions. Individually, each treatment will be extremely expensive, and in the aggregate their costs are projected to have a substantial impact on the affordability of health care. Stated frankly, health systems today are ill prepared to face the challenge of assessing and paying for the potential cures that will soon become available.

As the leading health technology assessment organization in the US, the Institute for Clinical and Economic Review (ICER) has completed reviews of three gene therapies and is in the midst of a fourth review. At this OHE lunchtime seminar, Steven Pearson, ICER’s President, will discuss the distinctive challenges in analysing the clinical and cost-effectiveness of these therapies, and the lessons learned to date. As part of this discussion, Dr Pearson will present the early outlines of options for new methods to calculate “value-based” prices for potential cures that offer magnitudes of health gains and future cost offsets that have never been generated by traditional treatments.

View the full seminar invite here.

The seminar will be held in the Sir Alexander Fleming Room, Southside, 7th Floor, 105 Victoria Street, London SW1E 6QT. A buffet lunch will be available from 12 p.m. The seminar will start promptly at 12:30 p.m. and finish promptly at 2 p.m.

OHE Lunchtime Seminar with Janel Hanmer on ‘An overview of the US National Institutes of Health (NIH) Patient Reported Outcomes Measurement Information System (PROMIS®) and the PROMIS-Preference (PROPr) scoring system’. To be held on 31st October 2018 from 12 p.m. to 2 p.m.

The EQ-5D, Health Utilities Index, SF-6D, and the Quality of Well-being Index are among the most widely used generic preference-based health-related quality of life measures. However, they have been found to have some limitations. The US NIH Patient Reported Outcomes Measurement Information System (PROMIS®) provides an opportunity to address several limitations of the existing generic preference measures including: (1) fully capturing the entire range of a construct, (2) measuring an individual’s health status with greater precision, and (3) creating a standardised valuation methodology for future studies. The PROMIS® measures stand to be highly applicable across clinical, research, and population studies. Thus, creating a preference-based scoring system for PROMIS would allow efficient use of study resources to collect both health profile and health utility scores.

Janel Hanmer is an Assistant Professor in the Department of Medicine at the University of Pittsburgh as well as being the Medical Director for Patient Reported Outcomes at the University of Pittsburgh Medical Center. She leads the effort to develop the PROMIS-Preference (PROPr) scoring system. Combining both psychometric theory and econometric theory, Dr Hanmer will discuss the creation of the PROPr scoring system. She will discuss how item-response theory (IRT) is used to create measures of health domains, the linking of IRT calibrated questions to multi-attribute utility theory scoring, and the resulting scoring system.

View the full seminar invite here.

The seminar will be held in the Marlborough Suite, St Ermin's Hotel, 2 Caxton St, Westminster, London SW1H 0QW. A buffet lunch will be available from 12 p.m. The seminar will start promptly at 12:30 p.m. and finish promptly at 2 p.m.

If you would like to attend one (or both) of the seminars mentioned above, please send an email to ohegeneral@ohe.org.

Please visit the events page of our website for more details.

Posted in EQ-5D and PROMs, Health Technology Assessment | Tagged Events