How to complete the crossword

• Click on any clue to highlight the corresponding cells in the crossword
• Click on the cell and type in your answer to enjoy the challenge.
• If the text turns green, you’re correct.
• If you see a red cross next to the clue, try again.
• And if you are really stuck, scroll down and reveal the answers!

About the Publication

Amyotrophic lateral sclerosis (ALS) is a rare, rapidly progressive neurodegenerative disease with devastating clinical and economic consequences. Despite its relatively low prevalence, ALS imposes a disproportionate burden on patients, caregivers, and healthcare systems due to its complex diagnosis, limited treatment options, and high resource utilisation.

This report presents a comprehensive commercial case for investing in ALS research and therapeutic development, highlighting the unmet need, socioeconomic burden, and market opportunity across seven major countries: the UK, US, Canada, France, Germany, Italy, and Australia.

Click below to reveal the answers

Answers

Across

2. Short name for disease-modifying therapies – DMTs

5. How ALS diagnosis often is – Delayed

8. What ALS stands for – AmyotrophicLateralSclerosis

10. The type of costs beyond healthcare – Societal

Down

1. The type of disease ALS is – Neurodegenerative

3. The nerve cells damaged in ALS – MotorNeurons

4. A measure combining quality and length of life – QALYs

6. What is lacking for early ALS diagnosis – Biomarkers

7. Short for Health Technology Assessment – HTA

9. What ALS represents a strong case for – Investment