OHE Publications

OHE releases a number of publications throughout the year, authored by OHE team members and/or outside experts. All are free for download as pdf files; hard copies of some publications are available upon request.

A description of the OHE publications categories.


 

Garau, M., Towse, A. and Danzon, P.

Occasional Paper
February 2011

This paper examines the potentially positive impact of differential pricing in Europe and the overall negative effects of international reference pricing (IRP) measures. The authors point out that IRP actually encourages higher prices in lower-income countries, can delay marketing/patient access in lower-price countries, and ultimately translates into less investment in R&D. Differential pricing assumes that countries with lower incomes should pay lower prices, encourages the earliest possible marketing in all countries, and provides incentives for innovation.

Towse, A., Devlin, N., Hawe, E. and Garrison, L.

Consulting Report
January 2011

This report examines and makes suggestions for the appropriate use of health technology assessment (HTA) in emerging markets. In particulary, it considers how the stage of development of the health care system affects the relevance and appropriate use of various types of HTA. The approach developed then is used to analyse the options for Brazil, China and Taiwan.

Grabowski, H.G.

Seminar Briefing
January 2011

Priority Review Vouchers (PRVs) are awarded in the US to companies that gain approval there for a new drug for one of sixteen tropical diseases, under a law passed in 2007. The PRV entitles the holder to priority review by the FDA of another drug of the bearer’s choice.  The Vouchers are transferable, i.e., not limited to use by the company that gained approval of the neglected-disease drug.  

Devlin, N., Buckingham, K., Shah, K., Tsuchiya, A., Tilling, C., Wilkinson, G. and van Hout, B.

Research Paper
December 2010

OHE was awarded a UK Department of Health grant to further develop three aspects of health status indexes.  Results of the second of these, advances in Time Trade Off (TTO) methodology, are reported in this OHE Research Paper.

Mattison, N., Mestre-Ferrandiz, J. and Towse, A. eds.

Monograph
December 2010

This publication reports on a seminar intended to encourage further thought about the distinguishing characteristics of the market for biosimilars and the implications of these for potential savings.

Economists and regulatory experts from the US and Europe were invited to describe their research and offer their perspectives about what can be expected in the near- and medium-term.  The publication includes updated insights that take account of changes since the seminar, including more recent analyses of potential market impact.

Martin, B.

Seminar Briefing
December 2010

Professor Ben Martin (Science and Technology Policy Studies at SPRU, University of Sussex) defines science policy research as ‘economic, policy, management and organisational studies of science, technology and innovation (STI) with a view to providing useful inputs to decision-makers concerned with policies for and the management of STI’.  The field is important because STI is important: it is a source of progress, a major contributor to the wealth of nations, provides the basis for new goods and services and for new capabilities, and contributes to changes in the quality of life and t

Mestre-Ferrandiz, J., Garau, M., O'Neill, P. and Sussex, J.

Consulting Report
November 2010

This report examines the effect of the European Union’s 1999 Regulation on Orphan Medicinal Products (OMPs) on the European economy and society.  This study collected data on several indicators of activity, completed a confidential survey of companies developing OMP, concluded four case studies and undertook a literature review.  The result is a rich tableau of data and information that describe the effects of the OMP Regulation in some detail.  Findings include the following.

O'Neill, P.

Monograph
November 2010

In December 2006, the National Institute for Health and Clinical Excellence (NICE) issued guidance for preventing and managing overweight and obesit. Recommendations are step-wise, starting with lifestyle changes and progressing through medicine to bariatric surgery. The guidance recommends that patients considered for bariatric surgery have either a BMI of 40 or more, or a BMI over 35 with an associated condition such as diabetes. Costing guidelines are included in the guidance.

Sussex, J., Shah, K. and Butler, J.

Consulting Report
October 2010

This research reviews how vaccines other than for travel or influenza are evaluated, procured and delivered in Australia. It includes observations as to whether and how the economic assessment process differs for vaccines compared to curative pharmaceutical products and implications of central purchasing for economic efficiency.

Sussex, J. and Shah, K.

Consulting Report
October 2010

This research reviews how vaccines other than for travel or influenza are evaluated, procured and delivered in the UK. It includes observations as to whether and how the economic assessment process differs for vaccines compared to curative pharmaceutical products and the implications of the current pricing approach.

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