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Born Imperfect: The role of genetic disease
1 January 1993
The area of genetics in relation to hereditary disease has become an important aspect of medical practice with potentially far-reaching ramifications. We all inherit many features from our parents such…
Genomics, Healthcare and Public Policy
1 October 1999
…with the School of Public Policy, University College London, and Pharmaceutical Partners for Better Healthcare, examined the status and likely consequences of healthcare applications of genetics. Advances in genetics will…
Cell & Gene Therapy
…solutions for diseases previously deemed untreatable. They hold immense potential in addressing genetic disorders, cancer, and other conditions by targeting the underlying causes at a cellular or genetic level, often…
Personalised Medicine: Is it an Oil-Rush or Oil-Spill?
3 February 2020, 12:00am
…genetic mutations and it is clear that genetic mutations rarely map 1-2-1 onto disease. Professor Alistair McGuire will present some preliminary thoughts on the promises offered by personalised medicine that…
Pharmacogenomics Testing: A Crucial Piece to Unlocking the Full Value of Medicines
5 June 2025
…medicines do not deliver their intended therapeutic benefits for the individuals taking them—due to genetic variations. Despite the tremendous benefits that innovative medicines have brought to patients, health systems, and…
Rare Disease Day 2024: Why Do We Care About Rare?
29 February 2024
…low, knowledge is scarce, and research is lacking. In addition, around 80% of rare diseases are of genetic origin, and 70% start in childhood. Spotting the signs and accessing genetic…
CBO Doesn’t Capture The Real Impact of H.R. 3 on Innovation
14 September 2021
…also led to a reduction in the average target patient population size. In 2020, 58% of new approvals were for rare or orphan diseases. Molecular and genetic techniques allow better…
OHE Lunchtime Seminar: Personalised Medicine: Is it an oil-rush or oil-spill?
16 January 2020
…general difficulty associated with personalised medicine. Generally, complex diseases are associated multiple genetic mutations and it is clear that genetic mutations rarely map 1-2-1 to disease. Professor Alistair McGuire…
Personalised Medicine: is it an Oil-Rush or Oil-Spill?
1 May 2020
Personalised medicine, also known as ‘precision’ or ‘stratified’ medicine, targets treatment by using genetics and/or biomarkers to identify patients or subgroups of patients who have distinct mechanisms of disease or…