OHE Publications

Monograph
September 1976

To present a balanced view of the brand name/generic controversy and the associated field of bioavailability. Many have discussed these problems; scientists, politicians, industrialists, legislators, hospital pharmacists, physicians, and clinical pharmacologists.

Series on Health
April 1976

Rabies, which is traditionally regarded as a mortal condition in humans once the symptoms have developed, is the best known and most feared of all the diseases which may be passed from animals to man. The course of the illness is usually extremely distressing, both physically and psychologically, although modem medicines can now help to relieve the suffering of its victims. Nevertheless there is still no effective cure. Awareness of this underlines the importance of preventive measures like immunisation and the control of rabies transmission amongst both wild and domestic animals.

Series on Health
February 1976

Anaesthesia is the art or science of rendering the patient unaware, thereby providing an indispensable foundation for surgery. Although man had unsuccessfully been attempting to eliminate the pain of surgical procedures for many centuries, anaesthesia was not introduced into medical practice until the first half of the nineteenth century.

Briefing
January 1976

During the last fifteen years the rate of homicides (which comprise all cases of murder, manslaughter and infanticide) occurring in England and Wales has doubled. Analysis of the ages of victims shows that the homicide rate is rising most rapidly amongst males in or around their twenties, over 15 per million of whom are now killed as a result of the deliberate acts of other persons each year.

Briefing
December 1975

In 1901 approximately 127,000 infants and 81,000 children aged 1-14 died in England and Wales. By 1973, the corresponding figures were 11,500 and 4,500, representing falls of 91 per cent and 94 per cent respectively. During this period the total number of persons aged 0-14 rose, albeit unsteadily, from 10.5 million (32 per cent of the total population) to 11.6 million (23 per cent).

Series on Health
October 1975

Mankind has used mind affecting drugs throughout and probably for many thousands of years before recorded history. In European culture alcohol, tobacco, caffeine and to a lesser extent opium have played particularly important roles as psychoactive agents; but in other parts of the world a wide variety of alternative intoxicants, stimulants and hallucinogens have been employed. These include cocaine, mescaline and cannabis.

Series on Health
August 1975

For the past 25 years the problems of the National Health Service in Britain have been considered primarily in terms of a shortage of resources. This emphasis has persisted in spite of National Health Service expenditure having doubled in real terms and in spite of huge increases in most grades of manpower. The number of doctors working in the hospitals, for example, has also doubled since 1948.

Monograph
July 1975

Health Economics delivered a paper to the Pharmaceutical Sciences Section of the Australian and New Zealand Association for the Advancement of Science at the Academy of Sciences in Canberra. The burden of this paper was that it was a fundamental misconception to believe that price competition was lacking in the prescription medicine market, at least in the context of the British National Health Service.

Series on Health
May 1975

The unequal geographical distribution of multiple sclerosis is one of its most striking and potentially significant characteristics. The disease occurs with much greater frequency in temperate latitudes and it is particularly prevalent on the island of Orkney, where the prevalence rate is about six times greater than the world average of 30 per 100,000 population (Donnelly 1974). In Great Britain as a whole it is estimated that between 40,000 and 50,000 individuals suffer from the illness, implying a rate of more than twice the world average figure.

Briefing
April 1975

At first sight it might seem disturbing that accidental deaths are contributing an increasing proportion of the total mortality amongst young people in the UK. In 1932, for example, approximately 6 per cent of all deaths in England and Wales in the 1-4 years old age group were due to accidents. By 1972 the proportion was 24 per cent. For the 5-14 age group the rise was from 12 per cent to 37 per cent and in the 15-24 year old age group 48 per cent of all deaths in 1972 were due to accidents compared with only 12 per cent in 1932. Yet in reality the picture is much more encouraging.

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