Research Paper

Shah, K., Praet, C., Devlin, N., Sussex, J., Appleby, J. and Parkin, D.

Research Paper
May 2011

The appraisal of health care technologies by the UK’s National Institute for Health and Clinical Excellent (NICE) focuses on cost effectiveness, usually measured in terms of incremental cost per quality adjusted life year (QALY) gained.  According to the findings presented in this Research Paper, however, cost effectiveness does not appear to be the dominant consideration in NHS decisions about resource allocation.

Towse, A. and Sharma, P.

Research Paper
April 2011

Antimicrobial resistance (AMR) is becoming a major global public health threat and has begun to command attention from European and US policy makers. An initial focus on monitoring AMR and conserving existing treatments by cutting down on misuse has been complemented by moves towards addressing the paucity of new drugs in the R&D pipeline of the pharmaceutical industry.

Watson, V., Sussex, J., Teeteh, E. and Ryan, M.

Research Paper
March 2011

The UK’s National Clinical Assessment Agency (NCAS) is designed specifically to provide advice on performance issues, on request, to NHS organisations employing or contracting with doctors, pharmacists, and dentists. Currently, the NCAS is financed from central NHS funds, not from charges to NHS organisations. By 2013, however, the NCAS is to become self-funding.

Devlin, N., Buckingham, K., Shah, K., Tsuchiya, A., Tilling, C., Wilkinson, G. and van Hout, B.

Research Paper
December 2010

OHE was awarded a UK Department of Health grant to further develop three aspects of health status indexes.  Results of the second of these, advances in Time Trade Off (TTO) methodology, are reported in this OHE Research Paper.

Garau, M., Shah, K., Mason, A.R., Wang, Q., Towse, A. and Drummond, M.F.

Research Paper
October 2010

Current methods for constructing quality adjusted life year (QALY) measurements may be deficient for cancer patients in three respects: descriptions of health state, valuation of health state, and the source of values upon which measures are based.

Existing measures of health are either not sensitive enough or not attuned to cancer patients’ actual preferences.  For example, evidence suggests that the EQ 5D instrument does not capture the small changes in health that often are very important to cancer patients.

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