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Challenges and Solutions for Budget Impact Analysis of Gene Therapies
10 March 2025
…a paradigm shift in medicine, offering the potential for significant improvements in both quality and longevity of life, by addressing the root genetic causes of diseases. Due to this potential…
OHE at ISPOR 2019
8 May 2019
…Clinical and Economic Value of Genetic Sequencing in Cancer Care: Are Next Generation Sequencing(Ngs)-based Tests Clinically Useful and Cost Effective in Real World Settings? What Is Necessary to Fully Realize…
Advancing Rare Disease Care: Challenges and Key Issues
28 February 2025
…7,000 (known) rare conditions, 80% of which have a genetic cause. The definition of “rare” means that a disease impacts fewer than one in 2,000 people, but the majority of…
OHE’s Towse on Challenges in Valuing Genomic Medicines
23 May 2013
…view other videos from the Translation Genomics Event presented by the NHS’s National Genetics Education and Development Centre click here. Challenges in Valuing Genomic Medicines from Office of Health Economics…
Lung Cancer’s Biggest Test: How Can We Mobilise NGS Testing to Transform Lung Cancer Care?
7 December 2023, 12:00am
…OHE. Lotte was the moderator for this session. She is a co-author of the report as well as expert in the field of economic evaluation of genetic diagnostics and precision…
Prevention in the NHS 10 Year Health Plan: Promise, limits, and the path forward
17 September 2025
…(identifying genetic risks), secondary (early detection) and tertiary (personalised treatment) prevention, which will also require coordination across laboratories, specialist care and community services. There is additional complexity added to this…
Amanda Cole
30 May 2014
…research agenda for how real-world evidence can improve healthcare technology development and adoption. Amanda has a special interest in rare diseases and serves on several advisory groups, including Genetic Alliance…
Health Technology Assessment of Gene Therapies: Are Our Methods Fit for Purpose?
1 June 2022
…known monogenic (single gene) cause. In contrast to traditional small molecule medicines, gene therapies have the potential to correct underlying genetic defects, offering the potential for transformational health gains rather…
OHE Lunchtime Seminar: Early Experience with HTA of Gene Therapies in the US: Pricing and Paying for Cures
21 October 2018, 11:00pm
…haemophilia, sickle cell disease, and numerous other genetically-based conditions. Individually, each treatment will be extremely expensive, and in the aggregate their costs are projected to have a substantial impact on…