Template-Type: ReDIF-Paper 1.0 Author-Name: Sam Large Author-Name: Joe Trim Author-Name: Ella Barker Author-Name: Louis Zanden Author-Name: Phill O’Neill Author-Name: Chris Sampson Title: The impact of inflation on incremental costs in HTA Abstract: Inflation reshapes the economic landscape in which new treatments are evaluated. Yet cost-effectiveness thresholds tend to remain fixed over time. This report examines how inflation in NHS healthcare costs associated with resource use affects the estimation of incremental costs in health technology assessment (HTA), and what this means for the cost‑effectiveness and commercial viability of new technologies when decision thresholds do not adjust accordingly. Throughout this paper, we distinguish between intervention costs (e.g. the price of treatments) and background NHS costs (i.e. healthcare resource use associated with delivering care related or unrelated to an intervention). Annual publications of NHS unit… Creation-Date: 2026-06-04 File-URL: https://www.ohe.org/publications/the-impact-of-inflation-on-incremental-costs-in-hta/ File-Format: text/html File-URL: https://www.ohe.org/wp-content/uploads/2026/05/Large-S.-et-al.-2026-The-impact-of-inflation-on-incremental-costs-in-HTA-1.pdf File-Format: application/pdf Classification-JEL: I1 Handle: RePEc:ohe:conres:002533